If you want a comfortable and reliable SUV, go with the Lexus. If you don't care about reliability as much and want a sportier driving experience, go with the Mercedes GLC. I'm not a big fan of the GLE as it is not as up-to-date as with the rest of the Mercedes lineup. The Acura RDX is also really old-feeling. The MDX will be the largest and most practical while also having decent reliability. The infotainment is from the late 2000s though. If it were my money I'd take the Lexus RX, but if you plan on a short ownership buy the GLC.

For a family, the MDX seats 7 or 6 with captains chairs and is the most pracitcal. It is pretty nimble, too, for the size with SH-AWD. The interior quality is not really on par with the rest of the segment. The RX is the second most practical for a family. If you only need 5 seats and a large cargo area, this would suit you better. The RX is the most comfortable and reliable SUV on your list.

'Consumer Reports': Skip BMW and Benz, buy a Buick

https://www.usatoday.com/story/money/cars/2014/07/22/bmw-buick-consumer-reports-score-regal/12988137/

At US$43,,000 for a 2017 the quietest and smoothest would be a Buick Envision Premium l. With it's Hyperstrut from suspension and among the twin-clutch AWD it achieved 55.5 mph in Consumer Reports emergency test or on par with Porsche Macan and Jaguar F-pace. Along with handling it has the best braking for it's segment according to Car & Driver testing. It is also quieter than a Lexus RX according to C&D. This same cuv at US $49,000 before discounts offer all electronic safety features including articulating headlights that are also adaptive high beams, cross traffic alert when backing up, vibrating safety seat, forward and backward collision alert and stopping....

It has real leather seats with heat front and rear, along with heated leather steering wheel. The tri-zone climate control will have you not freezing yourself while trying to keep your rear passengers cool like most of the other SUVs. Unlike most at this price it has cooled front seats. The HUD-heads up display is a nice feature where I keep the speedometwrfloating low on the windshield.

At a discounted $33,000 the Envision is over $10,000 less expensive than a Lexus NX200T where some of the options are not available at any price but are offered on the Buick.

The Cadillac XT5 is the next step up from the Buick and can offer similar features.

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Response from LectroFuel

1:20 am November 5, 2017

Response from NormT

9:15 am November 5, 2017

'Consumer Reports': Skip BMW and Benz, buy a Buick